Article
The role of RhoA kinase inhibition in human placenta-derived multipotent cells on neural phenotype and cell survival.
Biomaterials - 1 Apr 2013
Wang Chih-Hsiang, Wu Chia-Ching, Hsu Shan-Hui, Liou Jun-Yang, Li Yu-Wei, Wu Kenneth K, Lai Yiu-Kay, Yen B Linju
Abstract excerpt
Current advances in stem cell biology have brought much hope for therapy of neuro-degenerative diseases. However, neural stem cells (NSCs) are rare adult stem cells, and the use of non-NSCs requires efficient and high-yielding lineage-specific differentiation prior to transplantation for efficacy. We report on the efficient differentiation of placental-derived multipotent cells (PDMCs) into a neural phenotype...
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