Article
A common MicroRNA signature consisting of miR-133a, miR-139-3p, and miR-142-3p clusters bladder carcinoma in situ with normal umbrella cells.
The American journal of pathology - 1 Apr 2013
Jia Angela Y, Castillo-Martin Mireia, Domingo-Domenech Josep, Bonal Dennis M, Sánchez-Carbayo Marta, Silva Jose M, Cordon-Cardo Carlos
Abstract excerpt
miRNAs are small noncoding RNAs with critical roles in a large variety of biological processes such as development and tumorigenesis. miRNA expression profiling has been reported to be a powerful tool to classify tissue samples, including cancers, based on their developmental lineage. In this study, we have profiled the expression of miRNAs in bladder carcinoma in situ (CIS) and distinct cell compartments of the...
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