Article
Dysregulation of miRNAs in bladder cancer: altered expression with aberrant biogenesis procedure.
Oncotarget - 18 Apr 2017
Dong Fan, Xu Tianyuan, Shen Yifan, Zhong Shan, Chen Shanwen, Ding Qiang, Shen Zhoujun
Abstract excerpt
Aberrant expression profiles of miRNAs are widely observed in the clinical tissue specimens and urine samples as well as the blood samples of bladder cancer patients. These profiles are closely related to the pathological features of bladder cancer, such as the tumour stage/grade, metastasis, recurrence and chemo-sensitivity. MiRNA biogenesis forms the basis of miRNA expression and function, and its dysregulation...
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