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Article

Genetic determinants of macular pigments in women of the Carotenoids in Age-Related Eye Disease Study.

Investigative ophthalmology & visual science - 28 Mar 2013

Meyers Kristin J, Johnson Elizabeth J, Bernstein Paul S, Iyengar Sudha K, Engelman Corinne D, Karki Chitra K, Liu Zhe, Igo Robert P, Truitt Barbara, Klein Michael L, Snodderly D Max, Blodi Barbara A, Gehrs Karen M, Sarto Gloria E, Wallace Robert B, Robinson Jennifer, LeBlanc Erin S, Hageman Gregory, Tinker Lesley, Mares Julie A

Abstract excerpt

PURPOSE: To investigate genetic determinants of macular pigment optical density in women from the Carotenoids in Age-Related Eye Disease Study (CAREDS), an ancillary study of the Women's Health Initiative Observational Study. METHODS: 1585 of 2005 CAREDS participants had macular pigment optical density (MPOD) measured noninvasively using customized heterochromatic flicker photometry and blood samples genotyped...

Topics

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Aging
Carotenoids
Cross-Sectional Studies
Delta-5 Fatty Acid Desaturase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macular Degeneration

Retinal Pigments

Scavenger Receptors, Class B

Source

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Identifiers

PMID: 23404124
DOI: 10.1167/iovs.12-10867
PMCID: PMC3626525

Genes

ABCA1
ABCG5
ELOVL2
FADS1
FADS2
GSTP1
LIPC
RPE65
SCARB1

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