Article
Combined effect of mitochondrial DNA 5178 C/A polymorphism and alcohol consumption on estimated glomerular filtration rate in male Japanese health check-up examinees: a cross-sectional study.
BMC nephrology - 12 Feb 2013
Kokaze Akatsuki, Ishikawa Mamoru, Matsunaga Naomi, Karita Kanae, Yoshida Masao, Shimada Naoki, Ohtsu Tadahiro, Shirasawa Takako, Ochiai Hirotaka, Hoshino Hiromi, Takashima Yutaka
Abstract excerpt
BACKGROUND: Prevention of chronic kidney disease (CKD) is a major public health issue. Although several studies have been performed on the association between alcohol consumption and CKD or renal function, it remains controversial. Numerous genetic polymorphisms have been reported to be associated with CKD and kidney function. Mitochondrial DNA cytosine/adenine (Mt5178 C/A) polymorphism is associated with...
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