Article
Extracellular life cycle of ComS, the competence-stimulating peptide of Streptococcus thermophilus.
Journal of bacteriology - 1 Apr 2013
Gardan Rozenn, Besset Colette, Gitton Christophe, Guillot Alain, Fontaine Laetitia, Hols Pascal, Monnet Véronique
Abstract excerpt
In streptococci, ComX is the alternative sigma factor controlling the transcription of the genes encoding the genetic transformation machinery. In Streptococcus thermophilus, comX transcription is controlled by a complex consisting of a transcriptional regulator of the Rgg family, ComR, and a signaling peptide, ComS, which controls ComR activity. Following its initial production, ComS is processed, secreted, and...
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