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Article

A novel function for the competence inducing peptide, XIP, as a cell death effector of Streptococcus mutans.

FEMS microbiology letters - 1 Nov 2012

Wenderska Iwona B, Lukenda Nikola, Cordova Martha, Magarvey Nathan, Cvitkovitch Dennis G, Senadheera Dilani B

Abstract excerpt

In Streptococcus mutans, ComX, an alternative sigma factor, drives the transcription of the 'late-competence genes' required for genetic transformation. ComX activity is modulated by inputs from two signaling pathways, ComDE and ComRS, that respond to the competence-stimulating peptide (CSP) and the SigX-inducing peptide (XIP), respectively. In particular, the comRS, encoding the ComR regulatory protein and the...

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Identifiers

PMID: 22900705
DOI: 10.1111/j.1574-6968.2012.02660.x
PMCID: PMC4669055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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