Engrailed homeobox transcription factors as potential markers and targets in cancer.

Abstract excerpt

Engrailed (En) is a member of the homeobox gene family, which encodes a homeodomain-containing transcription factor that is essential during early development. The only known site of normal adult Engrailed protein (EN) expression is in the nervous system, and it has been implicated in the development of both young-onset Parkinson's disease as well as autism. Over-expression of EN has been linked to tumour...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autistic Disorder
• Share to Biomarkers, Tumor
• Share to Gene Expression Regulation, Developmental