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In Vitro Fertilization Alters Growth and Expression of Igf2/H19 and Their Epigenetic Mechanisms in the Liver and Skeletal Muscle of Newborn and Elder Mice1

7 Feb 2013

Abstract excerpt

Epidemiological studies have reported a higher incidence of growth disorders among newborns conceived by in vitro fertilization (IVF), suggesting that IVF may be disruptive to the process of embryonic and fetal growth. However, the long-term effects of IVF on the growth and molecular mechanisms remain unclear. Therefore, we evaluated the body weight of IVF mice from birth to the age of 1.5 yr. In addition, we...

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PMID: 23390160
DOI: 10.1095/biolreprod.112.106070

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