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Article

Characterization of phosphodiesterase 2A in human malignant melanoma PMP cells.

Oncology reports - 1 Apr 2013

Morita Hiroshi, Murata Taku, Shimizu Kasumi, Okumura Kenya, Inui Madoka, Tagawa Toshiro

Abstract excerpt

The prognosis for malignant melanoma is poor; therefore, new diagnostic methods and treatment strategies are urgently needed. Phosphodiesterase 2 (PDE2) is one of 21 phosphodiesterases, which are divided into 11 families (PDE1-PDE11). PDE2 hydrolyzes cyclic AMP (cAMP) and cyclic GMP (cGMP), and its binding to cGMP enhances the hydrolysis of cAMP. We previously...

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Identifiers

PMID: 23381931
DOI: 10.3892/or.2013.2260
PMCID: PMC3621658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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