Article
Chimerism studies using in situ hybridization for the Y chromosome after T cell-depleted bone marrow transplantation.
Bone marrow transplantation - 1 Apr 1990
Przepiorka D, Gonzales-Chambers R, Winkelstein A, Rosenfeld C, Shadduck R K
Abstract excerpt
In situ hybridization for the Y chromosome (Y-ISH) was used to monitor engraftment in 10 patients with hematological malignancies who had received T cell-depleted marrow transplants from sex-mismatched donors, seven of whom were only partially HLA-matched. In the three patients who engrafted, as the peripheral counts rose, the percentage of host peripheral blood and marrow mononuclear cells decreased steadily,...
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