Use of a probe to repeat sequence of the Y chromosome for detection of host cells in peripheral blood of bone marrow transplant recipients.

doi:10.1093/ajcp/95.2.201

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Article

Use of a probe to repeat sequence of the Y chromosome for detection of host cells in peripheral blood of bone marrow transplant recipients.

American journal of clinical pathology - 1 Feb 1991

Przepiorka D, Thomas E D, Durnam D M, Fisher L

Abstract excerpt

In situ hybridization for the Y chromosome (Y-ISH) was used to identify residual host cells in the peripheral blood of 51 recipients of sex-mismatched allogeneic marrow not depleted of T cells following conditioning with high-dose cyclophosphamide and total body irradiation (TBI). One patient who rejected the graft showed rapid reappearance of host cells after transient donor marrow engraftment. Host cells were...

Topics

Adolescent
Adult
Blood Cells
Bone Marrow Transplantation
Child
Child, Preschool
DNA Probes
Female
Genotype
Graft vs Host Disease
Granulocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Leukemia

Leukocyte Count

Leukocytes, Mononuclear

Male

Middle Aged

Nucleic Acid Hybridization

Source

Open in PubMed

Identifiers

PMID: 1992610
DOI: 10.1093/ajcp/95.2.201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1992610-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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