Article
Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges.
The journal of pain - 1 Feb 2013
Bruehl Stephen, Apkarian A Vania, Ballantyne Jane C, Berger Ann, Borsook David, Chen Wen G, Farrar John T, Haythornthwaite Jennifer A, Horn Susan D, Iadarola Michael J, Inturrisi Charles E, Lao Lixing, Mackey Sean, Mao Jianren, Sawczuk Andrea, Uhl George R, Witter James, Woolf Clifford J, Zubieta Jon-Kar, Lin Yu
Abstract excerpt
UNLABELLED: Use of opioid analgesics for pain management has increased dramatically over the past decade, with corresponding increases in negative sequelae including overdose and death. There is currently no well-validated objective means of accurately identifying patients likely to experience good analgesia with low side effects and abuse risk prior to initiating opioid therapy. This paper discusses the concept...
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