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Article

Next-generation sequencing in understanding complex neurological disease.

Expert review of neurotherapeutics - 1 Feb 2013

Handel Adam E, Disanto Giulio, Ramagopalan Sreeram V

Abstract excerpt

Next-generation sequencing techniques have made vast quantities of data on human genomes and transcriptomes available to researchers. Huge progress has been made towards understanding the basis of many Mendelian neurological conditions, but progress has been considerably slower in complex neurological diseases (multiple sclerosis, migraine, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis,...

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Identifiers

PMID: 23368808
DOI: 10.1586/ern.12.165
PMCID: PMC3836167

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