Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Next generation sequencing for neurological diseases: new hope or new hype?

Clinical neurology and neurosurgery - 1 Jul 2013

Keogh M J, Chinnery P F

Abstract excerpt

Over the past year huge advances have been made in our ability to determine the genetic aetiology of many neurological diseases through the utilisation of next generation sequencing platforms. This technology is, on a daily basis, providing new breakthroughs in neurological disease. The aim of this article is to clearly describe the technological platforms, methods of data analysis, established breakthroughs, and...

Topics

Data Interpretation, Statistical
Exome
Genomics
High-Throughput Nucleotide Sequencing
Humans
Mutation
Nervous System Diseases
Sequence Analysis, DNA

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23200550
DOI: 10.1016/j.clineuro.2012.09.030
PMCID: PMC3694302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next generation sequencing for neurological diseases: new hope or new hype?PMID 23200550Read ↗

Next-generation sequencing diagnostics for neurological diseases/disorders: from a clinical perspective.Semantic proximity Read ↗

Use of next-generation sequencing and other whole-genome strategies to dissect neurological disease.Semantic proximity Read ↗

Next-generation sequencing in understanding complex neurological disease.Semantic proximity Read ↗

Whole-genome and whole-exome sequencing in neurological diseases.Semantic proximity Read ↗

Current scenario of the genetic testing for rare neurological disorders exploiting next generation sequencingSemantic proximity Read ↗

Next generation sequencing techniques in neurological diseases: redefining clinical and molecular associations.Semantic proximity Read ↗

Advances in genetic diagnosis of neurological disorders.Semantic proximity Read ↗

Application of Next-Generation Sequencing in Neurodegenerative Diseases: Opportunities and Challenges.Semantic proximity Read ↗

What we have learned from the next-generation sequencing: Contributions to the genetic diagnoses and understanding of pathomechanisms of neurodegenerative diseases.Semantic proximity Read ↗

Clinical application of next-generation sequencing to the practice of neurologySemantic proximity Read ↗

Unraveling the Genetic Landscape of Neurological Disorders: Insights into Pathogenesis, Techniques for Variant Identification, and Therapeutic ApproachesSemantic proximity Read ↗

Genetic analysis in neurology: the next 10 years.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.