Article
Association of vascular endothelial growth factor gene polymorphisms with behcet disease in a Korean population.
Human immunology - 1 Oct 2005
Nam Eon Jeong, Han Seung Woo, Kim Sung Uk, Cho Jang Hee, Sa Kheum Hee, Lee Won Kee, Park Jae Yong, Kang Young Mo
Abstract excerpt
Vascular endothelial growth factor (VEGF) is important for angiogenesis and inflammation, both of which are codependent and contribute to the pathophysiology of Behcet disease (BD). The increased expressions of VEGF have been observed in the active stage and in the ocular inflammation of BD. Polymorphisms of the VEGF gene have been associated with chronic inflammatory disease including rheumatoid arthritis. We...
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