Article
Role of the vitamin K epoxide reductase complex subunit 1 (VKORC1) -1639G>A gene polymorphism in patients with retinal vein occlusion.
Current eye research - 1 Dec 2013
Weger Martin, Steinbrugger Iris, Renner Wilfried, Pöschl Eva Maria, Brockmann Tobias, Rabensteiner Dieter Franz, El-Shabrawi Yosuf, Haas Anton
Abstract excerpt
PURPOSE OF THE STUDY: Retinal vein occlusion (RVO) is a major vision-threatening disease. Vitamin K epoxide reductase recycles reduced vitamin K, which is essential for the gamma carboxylation of clotting factors II, VII, IX, X and proteins C and S. Recently, the vitamin K epoxide reductase complex subunit 1 (VKORC1) -1639G>A (rs9923231) polymorphism has been reported as a novel risk factor for RVO in a Turkish...
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