Article
The dentin matrix acidic phosphoprotein 1 (DMP1) in the light of mammalian evolution.
Journal of molecular evolution - 1 Feb 2013
Silvent Jérémie, Sire Jean-Yves, Delgado Sidney
Abstract excerpt
Dentin matrix acidic phosphoprotein 1 (DMP1) is an acidic, highly phosphorylated, noncollagenous protein secreted during dentin and bone formation. Previous functional studies of DMP1 have revealed various motifs playing a role in either mineralization or cell differentiation. We performed an evolutionary analysis of DMP1 to identify residues and motifs that were conserved during 220 millions years (Ma) of...
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