Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.

Neoplasia (New York, N.Y.) - 1 Jan 2013

Jin Guangfu, Zheng Siqun Lilly, Lilja Hans, Kim Seong-Tae, Tao Sha, Gao Zhengrong, Young Tracey, Wiklund Fredrik, Feng Junjie, Isaacs William B, Rittmaster Roger S, Gronberg Henrik, Condreay Lynn D, Sun Jielin, Xu Jianfeng

Abstract excerpt

BACKGROUND: Percentage of free-to-total prostate-specific antigen (%fPSA) is an independent predictor of risk for prostate cancer among men with modestly elevated level of total PSA (tPSA) in blood. Physiological and pathological factors have been shown to influence the %fPSA value and diagnostic accuracy. MATERIALS/METHODS: To evaluate genetic determinants of %fPSA, we conducted a genome-wide association study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Prostate-Specific Antigen

Share to Prostatic Neoplasms

Share to Repressor Proteins

Share to Sweden

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23359319
DOI: 10.1593/neo.121620
PMCID: PMC3556942

Genes

KLK2
KLK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.PMID 23359319Read ↗

Genetic variation in KLK2 and KLK3 is associated with concentrations of hK2 and PSA in serum and seminal plasma in young men.Semantic proximity Read ↗

Prostate Cancer Risk-Associated Single-Nucleotide Polymorphism Affects Prostate-Specific Antigen Glycosylation and Its FunctionSemantic proximity Read ↗

Genetic correction of PSA values using sequence variants associated with PSA levels.Semantic proximity Read ↗

Search for genetic factor association with cancer-free prostate-specific antigen level elevation on the basis of a genome-wide association study in the Korean population.Semantic proximity Read ↗

Genetic polymorphisms at 19q13.33 are associated with [-2]proPSA (p2PSA) levels and provide additional predictive value to prostate health index for prostate cancer.Semantic proximity Read ↗

The Stockholm3 blood-test predicts clinically-significant cancer on biopsy: independent validation in a multi-center community cohort.Semantic proximity Read ↗

A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer.Semantic proximity Read ↗

Biochemical activity induced by a germline variation in KLK3 (PSA) associates with cellular function and clinical outcome in prostate cancerSemantic proximity Read ↗

Kallikreins as Biomarkers for Prostate CancerSemantic proximity Read ↗

Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.