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Article

TGF-β1 T869C polymorphism may affect susceptibility to idiopathic pulmonary fibrosis and disease severity.

Lung - 1 Apr 2013

Son Ji Young, Kim Song Yee, Cho Sang Ho, Shim Hyo Sub, Jung Ji-Ye, Kim Eun Young, Lim Ju Eun, Park Byung Hoon, Kang Young Ae, Kim Young Sam, Kim Se Kyu, Chang Joon, Park Moo Suk

Abstract excerpt

BACKGROUND: Transforming growth factor-β1 (TGF-β1) is a key cytokine that plays a critical role in idiopathic pulmonary fibrosis (IPF). The genotypes of T869C polymorphism may be associated with the susceptibility to fibrotic lung disease. METHODS: We investigated a single-nucleotide polymorphism at exon 1 nucleotide position 29 (T → C) of the TGF-β1 gene. Eighty-five healthy controls and 85 subjects with...

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PMID: 23344525
DOI: 10.1007/s00408-012-9447-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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