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Article

Expression and copy number gains of the RET gene in 631 early and mid stage non-small cell lung cancer cases.

Thoracic cancer - 1 Apr 2018

Tan Ling, Hu Yerong, Tao Yongguang, Wang Bin, Xiao Jun, Tang Zhenjie, Lu Ting, Tang Hao

Abstract excerpt

BACKGROUND: To identify whether RET is a potential target for NSCLC treatment, we examined the status of the RET gene in 631 early and mid stage NSCLC cases from south central China. METHODS: RET expression was identified by Western blot. RET-positive expression samples were verified by immunohistochemistry. RET gene mutation, copy number variation, and rearrangement were analyzed by DNA Sanger sequencing, TaqMan...

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Topics

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Share to Anaplastic Lymphoma Kinase
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Kinesins

Share to Oncogene Proteins, Fusion

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Share to Proto-Oncogene Proteins c-ret

Source

Open in PubMed Open full text

Identifiers

PMID: 29473341
DOI: 10.1111/1759-7714.12603
PMCID: PMC5879055

Genes

RET
ALK
EGFR
ROS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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