Article
Total and high molecular weight adiponectin and level-modifying polymorphisms of ADIPOQ in centenarians.
Endokrynologia Polska - 1 Jan 2012
Roszkowska-Gancarz Małgorzata, Bartoszewicz Zbigniew, Polosak Jacek, Kurylowicz Alina, Jonas Marta, Mossakowska Małgorzata, Franek Edward, Puzianowska-Kuźnicka Monika
Abstract excerpt
INTRODUCTION: Adiponectin demonstrates a protective role against the development of obesity, type 2 diabetes mellitus, and cardiovascular disease. The -11377C 〉 G, -11391G 〉 A, and -11426A 〉 G promoter polymorphisms of ADIPOQ gene influence the level of circulating adiponectin. We examined the level of total and high molecular weight (HMW) adiponectin in centenarians and associated it with biochemical parameters....
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