Article
Angular homeostasis: VI. Threshold processes with bivariate liabilities.
American journal of medical genetics - 1 May 1990
Murphy E A, Berger K R, Pyeritz R E, Sagawa Y
Abstract excerpt
The general structure of the threshold model of multifactorial determination is discussed. It is supposed that in place of a single liability (in Falconer's sense) there are two separate liabilities; and whether or not the pathological trait is present depends on a non-additive interaction between the liabilities, so that the region has curved boundaries. The genetics of ontogeny of a process involving spatial...
Topics
- Embryonic and Fetal Development
- Female
- Homeostasis
- Humans
- Male
- Models, Genetic
- Phenotype
- Probability