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Article

EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF

21 Jan 2013

Abstract excerpt

Understanding tumor-induced angiogenesis is a challenging problem with important consequences for the diagnosis and treatment of cancer. In this study, we define a novel function for epithelial membrane protein-2 (EMP2) in the control of angiogenesis. EMP2 functions as an oncogene in endometrial cancer, and its expression has been linked to decreased survival. Using endometrial cancer xenografts, modulation of...

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PMID: 23334331
DOI: 10.1038/onc.2012.622

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