Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways.

Journal of translational medicine - 29 May 2013

Su Yajuan, Gao Lingjuan, Teng Lichen, Wang Ying, Cui Jialin, Peng Shiyun, Fu Songbin

Abstract excerpt

BACKGROUND: Endothelial progenitor cells (EPCs) contribute to tumor angiogenesis and growth. We previously reported that over-expression of an inhibitor of DNA binding/differentiation 1 (Id1) in EPCs can enhance EPC proliferation, migration, and adhesion. In this study, we investigated the role of Id1 in EPC angiogenesis in patients with ovarian cancer and the underlying signaling pathway. METHODS: Circulating...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endothelial Cells
Share to Matrix Metalloproteinase 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to NF-kappa B

Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins c-akt

Share to RNA, Small Interfering

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 23714001
DOI: 10.1186/1479-5876-11-132
PMCID: PMC3687679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Id1 enhances human ovarian cancer endothelial progenitor cell angiogenesis via PI3K/Akt and NF-κB/MMP-2 signaling pathways.PMID 23714001Read ↗

MicroRNA-133a-5p Promotes Angiogenesis of Endothelial Progenitor Cells via TRIM59/Id1 in Ovarian CancerSemantic proximity Read ↗

Effects of PELP1 on proliferation,metastasis and angiogenesis of epithelial ovarian cancerSemantic proximity Read ↗

MicroRNA-133a-5p Promotes Angiogenesis of Endothelial Progenitor Cells via TRIM59/Id1 in Ovarian CancerSemantic proximity Read ↗

ANGPTL4 regulates ovarian cancer progression by activating the ERK1/2 pathwaySemantic proximity Read ↗

MiR-148b-3p inhibits renal carcinoma cell growth and pro-angiogenic phenotype of endothelial cell potentially by modulating FGF2.Semantic proximity Read ↗

Prospero‐related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating interleukin‐8 expressionSemantic proximity Read ↗

Identification of novel targets for antiangiogenic therapy by comparing the gene expressions of tumor and normal endothelial cellsSemantic proximity Read ↗

Identifying and targeting angiogenesis-related microRNAs in ovarian cancerSemantic proximity Read ↗

Down-regulation of PADI2 prevents proliferation and epithelial-mesenchymal transition in ovarian cancer through inhibiting JAK2/STAT3 pathway in vitro and in vivo, alone or in combination with OlaparibSemantic proximity Read ↗

ESM1/VEGFα signaling pathway augments endothelial cell proliferation and tumor angiogenesis in human cervical squamous cell carcinomaSemantic proximity Read ↗

Prognostic role of expression of angiogenesis markers in hepatocellular carcinoma: A bioinformatics analysisSemantic proximity Read ↗

LncRNA WTAPP1 Promotes Migration and Angiogenesis of Endothelial Progenitor Cells via MMP1 Through MicroRNA 3120 and Akt/PI3K/Autophagy PathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.