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Article

Phenotypic heterogeneity in the NCI-H125 cell line affects biological activity using the epidermal growth factor receptor as target.

Acta pharmaceutica (Zagreb, Croatia) - 1 Dec 2012

Blanco Rancés, Cedeño Mercedes, González Narjara, Rodríguez Reynier, Sánchez Javier, Rengifo Enrique

Abstract excerpt

We evaluated the influence of some morphological changes of the NCI-H125 cell line in surface expression of the epidermal growth factor receptor (EGFR) and their impact on some biological activity assays using this molecule as target. Hematoxylin and eosin (H/E) staining, light microscopy immunocytochemistry, flow cytometric antibody-receptor binding test, cell viability determination and cell cycle analysis were...

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Identifiers

PMID: 23333890
DOI: 10.2478/v10007-012-0038-6

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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