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Article

Spliceosome mutations in myelodysplastic syndromes and chronic myelomonocytic leukemia.

Oncotarget - 1 Nov 2012

Chesnais Virginie, Kosmider Olivier, Damm Frederik, Itzykson Raphael, Bernard Olivier A, Solary Eric, Fontenay Michaela

Abstract excerpt

The recently discovered spliceosome mutations represent a group of acquired genetic alterations that affect both myeloid and lymphoid malignancies. A substantial proportion of patients with myelodysplastic syndromes (MDS), chronic myelomonocytoic leukemia (CMML) or chronic lymphocytic leukemia (CLL) harbor such mutations, which are often missense in type. Genotype-phenotype correlations have been observed,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23327988
DOI: 10.18632/oncotarget.749
PMCID: PMC3717792

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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