Article
Distinct genomic organization, mRNA expression and cellular localization of members of two amastin sub-families present in Trypanosoma cruzi.
BMC microbiology - 17 Jan 2013
Kangussu-Marcolino Monica Mendes, de Paiva Rita Márcia Cardoso, Araújo Patrícia Rosa, de Mendonça-Neto Rondon Pessoa, Lemos Laiane, Bartholomeu Daniella Castanheira, Mortara Renato A, daRocha Wanderson Duarte, Teixeira Santuza Maria Ribeiro
Abstract excerpt
BACKGROUND: Amastins are surface glycoproteins (approximately 180 residues long) initially described in Trypanosoma cruzi as particularly abundant during the amastigote stage of this protozoan parasite. Subsequently, they have been found to be encoded by large gene families also present in the genomes of several species of Leishmania and in other Trypanosomatids. Although most amastin genes are organized in...
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