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Intestinal T-cell Responses in Celiac Disease – Impact of Celiac Disease Associated Bacteria

9 Jan 2013

Abstract excerpt

A hallmark of active celiac disease (CD), an inflammatory small-bowel enteropathy caused by permanent intolerance to gluten, is cytokine production by intestinal T lymphocytes. Prerequisites for contracting CD are that the individual carries the MHC class II alleles HLA-DQ2 and/or HLA-DQ8 and is exposed to gluten in the diet. Dysbiosis in the resident microbiota has been suggested to be another risk factor for...

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PMID: 23326425
DOI: 10.1371/journal.pone.0053414

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