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Article

Identification and characterization of TGFβ-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus

1 Jan 2009

Abstract excerpt

Chondroitin-4-sulfotransferase-1(C4ST-1)/carbohydrate sulfotransferase 11 (CHST11) is a Golgi-bound enzyme involved in the biosynthesis of the glycosaminoglycan chondroitin sulfate. The sulfation pattern of chondroitin is tightly regulated during development, injury and disease, with the temporal and spatial expression of chondroitin sulfotransferase genes believed to be a crucial determinant of the fine balance...

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PMID: 19937589
DOI: 10.4238/vol8-4gmr673

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