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Article

Structure and dynamic regulation of Abl kinases.

The Journal of biological chemistry - 22 Feb 2013

Panjarian Shoghag, Iacob Roxana E, Chen Shugui, Engen John R, Smithgall Thomas E

Abstract excerpt

The c-abl proto-oncogene encodes a unique protein-tyrosine kinase (Abl) distinct from c-Src, c-Fes, and other cytoplasmic tyrosine kinases. In normal cells, Abl plays prominent roles in cellular responses to genotoxic stress as well as in the regulation of the actin cytoskeleton. Abl is also well...

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Identifiers

PMID: 23316053
DOI: 10.1074/jbc.R112.438382
PMCID: PMC3581414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23316053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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