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Article

Genetic determinants of idiopathic noncirrhotic portal hypertension in HIV-infected patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Apr 2013

Vispo Eugenia, Cevik Muge, Rockstroh Juergen K, Barreiro Pablo, Nelson Mark, Scourfield Andrew, Boesecke Christoph, Wasmuth Jan-Christian, Soriano Vincent

Abstract excerpt

BACKGROUND: Noncirrhotic portal hypertension (NCPH) is a rare but potentially life-threatening complication in patients with human immunodeficiency virus (HIV). Cases of NCPH have been reported in HIV-negative individuals as result of treatment with thiopurines for leukemia or inflammatory bowel disease. Exposure to didanosine, which is also a purine analogue, predisposes to NCPH in the HIV setting. However, it...

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PMID: 23315321
DOI: 10.1093/cid/cit001

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