Article
Tumor burden is predictive of survival in patients with non-small-cell lung cancer and with activating epidermal growth factor receptor mutations who receive gefitinib.
Clinical lung cancer - 1 Jul 2013
Park Jin Hyun, Kim Tae Min, Keam Bhumsuk, Jeon Yoon Kyung, Lee Se-Hoon, Kim Dong-Wan, Chung Doo Hyun, Kim Young Tae, Kim Young Whan, Heo Dae Seog
Abstract excerpt
BACKGROUND: Although activating epidermal growth factor receptor (EGFR) mutations are excellent predictors of gefitinib outcome in non-small-cell lung cancer (NSCLC), most patients become resistant to gefitinib. Despite our knowledge of the molecular basis of acquired resistance, clinical predictors have not been well elucidated. This study was undertaken to evaluate predictors of clinical outcome in patients...
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