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Liquid Biopsy and 18F-FDG PET/CT Derived Parameters as Predictive Factors of Osimertinib Treatment in Advanced EGFR-Mutated NSCLC.

Clinical lung cancer - 1 Dec 2024

Leonetti Alessandro, Cervati Veronica, Minari Roberta, Scarlattei Maura, Verzè Michela, Peroni Marianna, Pluchino Monica, Bonatti Francesco, Perrone Fabiana, Mazzaschi Giulia, Cosenza Agnese, Gnetti Letizia, Bordi Paola, Ruffini Livia, Tiseo Marcello

Abstract excerpt

OBJECTIVES: Despite the outstanding results achieved by osimertinib for the treatment of advanced EGFR-mutated NSCLC, the development of resistance is almost inevitable. While molecular mechanism responsible for osimertinib resistance are being mostly revealed, the definition of predictive biomarkers is crucial in order to identify patients at higher risk of progression and optimize treatment strategy. MATERIALS...

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PMID: 39198088
DOI: 10.1016/j.cllc.2024.07.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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