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Article

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression.

Journal of autoimmunity - 1 Mar 2013

de la Rica Lorenzo, Urquiza José M, Gómez-Cabrero David, Islam Abul B M M K, López-Bigas Nuria, Tegnér Jesper, Toes René E M, Ballestar Esteban

Abstract excerpt

Autoimmune rheumatic diseases are complex disorders, whose etiopathology is attributed to a crosstalk between genetic predisposition and environmental factors. Both variants of autoimmune susceptibility genes and environment are involved in the generation of aberrant epigenetic profiles in a cell-specific manner, which ultimately result in dysregulation of expression. Furthermore, changes in miRNA expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23306098
DOI: 10.1016/j.jaut.2012.12.005

Genes

CAPN8
DPP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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