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Article

Genetic mouse models to study blood–brain barrier development and function

1 Jan 2013

Abstract excerpt

The blood-brain barrier (BBB) is a complex physiological structure formed by the blood vessels of the central nervous system (CNS) that tightly regulates the movement of substances between the blood and the neural tissue. Recently, the generation and analysis of different genetic mouse models has allowed for greater understanding of BBB development, how the barrier is regulated during health and its response to...

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PMID: 23305182
DOI: 10.1186/2045-8118-10-3

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