Article
EGFR-directed monoclonal antibodies in non-small cell lung cancer.
Targeted oncology - 1 Mar 2013
Pirker Robert
Abstract excerpt
Several monoclonal antibodies directed against the epidermal growth factor receptor (EGFR) have been evaluated in patients with non-small cell lung cancer (NSCLC). Cetuximab, a chimeric monoclonal antibody, has been studied in combination with first-line chemotherapy in phase II and two phase III trials in patients with advanced NSCLC. The phase III FLEX trial demonstrated an increase in survival for...
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