Article
Modelling of genetic interactions improves prediction of hybrid patterns--a case study in domestic fowl.
Genetics research - 1 Oct 2012
Álvarez-Castro José M, Le Rouzic Arnaud, Andersson Leif, Siegel Paul B, Carlborg Örjan
Abstract excerpt
A major challenge in complex trait genetics is to unravel how multiple loci and environmental factors together cause phenotypic diversity. Both first (F(1)) and second (F(2)) generation hybrids often display phenotypes that deviate from what is expected under intermediate inheritance. We have here studied two chicken F(2) populations generated by crossing divergent chicken lines to assess how epistatic loci,...
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