Article
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension.
Respiratory research - 9 Jan 2013
Pfarr Nicole, Fischer Christine, Ehlken Nicola, Becker-Grünig Tabea, López-González Vanesa, Gorenflo Matthias, Hager Alfred, Hinderhofer Katrin, Miera Oliver, Nagel Christian, Schranz Dietmar, Grünig Ekkehard
Abstract excerpt
BACKGROUND: Aim of this prospective study was to compare clinical and genetic findings in children with idiopathic or heritable pulmonary arterial hypertension (I/HPAH) with children affected with congenital heart defects associated PAH (CHD-APAH). METHODS: Prospectively included were 40 consecutive children with invasively diagnosed I/HPAH or CHD-APAH and 117 relatives. Assessment of family members, pedigree...
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