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Article

World of Reproductive Biology

1 Jan 2013

Abstract excerpt

BOR–Papers in Press published 3 October 2012 DOI: 10.1095/biolreprod.112.105338 A study in mice points to a new approach to preserving fertility in female cancer patients. Chemotherapy can wreak havoc on DNA. The drugs can damage the DNA of the oocyte pool, resulting in the induction of a cell-death program and culling of primordial oocytes, which provide a lifetime's supply of eggs. A consequence of cancer...

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PMID: 23288316
DOI: 10.1095/biolreprod.112.105957

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