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Article

Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry.

BMC systems biology - 1 Jan 2012

Chen Xin, Wu Qiong, Sun Ruimin, Zhang Louxin

Abstract excerpt

BACKGROUND: The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is stil...

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PMID: 23282116
DOI: 10.1186/1752-0509-6-S2-S5
PMCID: PMC3521188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23282116-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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