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The Longevity of Sirtuins

1 Dec 2012

Abstract excerpt

Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.

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Identifiers

PMID: 23273894
DOI: 10.1016/j.celrep.2012.12.004

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