Article
[Analysis of the MTHFR gene linkage disequilibrium structure and association of polymorphic gene variants with coronary atherosclerosis].
Genetika - 1 Oct 2012
Trifonova E A, Spiridonova M G, Gabidulina T V, Urnov F D, Puzyrev V P, Stepanov V A
Abstract excerpt
Analysis of the genome-specific linkage disequilibrium patterns in certain populations is a highly promising approach to the identification of functional variants that underlie susceptibility to complex diseases. In the present study, the linkage disequilibrium patterns of the methylenetetrahydrofolate reductase gene (MTHFR) were examined in a group of patients with coronary atherosclerosis (coronary artery...
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