Article
Characterization of the interstitial cellular infiltrate in experimental chronic cyclosporine nephropathy.
Transplantation - 1 Apr 1990
Gillum D M, Truong L, Tasby J
Abstract excerpt
In a recently described rodent model of chronic cyclosporine nephropathy (CCN) (consisting of irregularly distributed areas of interstitial inflammation, interstitial fibrosis, and tubular atrophy) we have characterized the interstitial inflammatory cells. Using a modified avidin-biotin peroxidase technique, kidney tissue was examined with monoclonal antibodies directed against leukocyte-common antigen (LCA), T...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Surface
- Connective Tissue Cells
- Cyclosporins
- Cytoplasm
- Disease Models, Animal
- Kidney Diseases
- Leukocytes, Mononuclear
- Macrophages
- Male