Article
Using genetics to enable studies on the prevention of Alzheimer's disease.
Clinical pharmacology and therapeutics - 1 Feb 2013
Crenshaw D G, Gottschalk W K, Lutz M W, Grossman I, Saunders A M, Burke J R, Welsh-Bohmer K A, Brannan S K, Burns D K, Roses A D
Abstract excerpt
Curing Alzheimer's disease (AD) remains an elusive goal; indeed, it may even prove to be impossible, given the nature of the disease. Although modulating disease progression is an attractive target and will alleviate the burden of the most severe stages, this strategy will not reduce the prevalence of the disease itself. Preventing or (as described in this article) delaying the onset of cognitive impairment and...
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