Article
Construction of human BMP2-IRES-HIF1αmu adenovirus expression vector and its expression in mesenchymal stem cells.
Molecular medicine reports - 1 Feb 2013
Liu Danping, Hu Liang, Zhang Zheng, Li Quan Ying, Wang Guoxian
Abstract excerpt
The present study aimed to construct a novel recombinant adenovirus expression vector Ad-BMP2-IRES-HIF1αmu that expresses human bone morphogenetic protein (BMP2) and mutant hypoxia-inducible factor 1α, and investigated its effects in promoting neogenesis of bone and angiogenesis. The recombinant adenovirus BMP2, HIF1αmu and pIRES2-EGFP expression vectors were constructed and transfected into HEK293A cells. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
