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Article

microRNA-21 Regulates Astrocytic Response Following Spinal Cord Injury

12 Dec 2012

Abstract excerpt

Astrogliosis following spinal cord injury (SCI) involves an early hypertrophic response that serves to repair damaged blood-brain barrier and a subsequent hyperplastic response that results in a dense scar that impedes axon regeneration. The mechanisms regulating these two phases of astrogliosis are beginning to be elucidated. In this study, we found that microRNA-21 (miR-21) increases in a time-dependent manner...

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PMID: 23238710
DOI: 10.1523/jneurosci.3860-12.2012

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