Article
Genetic and epigenetic variants influencing the development of nonalcoholic fatty liver disease.
World journal of gastroenterology - 7 Dec 2012
Li Yu-Yuan
Abstract excerpt
Nonalcoholic fatty liver disease (NAFLD) is common worldwide. The importance of genetic and epigenetic changes in etiology and pathogenesis of NAFLD has been increasingly recognized. However, the exact mechanism is largely unknown. A large number of single nucleotide polymorphisms (SNPs) related to NAFLD has been documented by candidate gene studies (CGSs). Among these genes, peroxisome proliferatoractivated...
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