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Discovery and verification of panels of T-lymphocyte proteins as biomarkers of Parkinson's disease

11 Dec 2012

Abstract excerpt

The diagnosis of Parkinson's disease (PD) is currently based on the clinical evaluation of extrapyramidal signs with a considerable error rate. The identification of specific markers might allow PD diagnosis before the onset of classical motor symptoms. By two-dimensional electrophoresis we identified proteome alterations in T-lymphocytes of 17 control subjects and 15 PD patients. The observed changes were used...

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PMID: 23233872
DOI: 10.1038/srep00953

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