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Article

Purpurin Suppresses Candida albicans Biofilm Formation and Hyphal Development

30 Nov 2012

Abstract excerpt

A striking and clinically relevant virulence trait of the human fungal pathogen Candida albicans is its ability to grow and switch reversibly among different morphological forms. Inhibition of yeast-to-hypha transition in C. albicans represents a new paradigm for antifungal intervention. We have previously demonstrated the novel antifungal activity of purpurin against Candida fungi. In this study, we extended our...

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PMID: 23226409
DOI: 10.1371/journal.pone.0050866

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